EPA METHOD 8327

The dilute-and-shoot liquid chromatography/tandem mass spectrometry (LC/MS/MS) method, known as US EPA Method 8327, enables swift analysis of 24 PFAS in non-potable waters like surface water, groundwater, and wastewater. Aligned with ASTM method D7979 protocols, it employs Multiple Reaction Monitoring (MRM) for improved selectivity, and quantification is achieved through external calibration.

technical data sheet

METHOD CODE
LAB-TM-079
EQUIPMENT
Ultra-Performance Liquid Chromatography /
Tandem Mass Spectrometry (UPLC-MS/MS)
METHOD REFERENCE
EPA Method 8327
REPORTABLE UNIT
ng/L
SAMPLE SIZE REQUIREMENTS
3x 20 mL
AVAILABLE FOR
Non-potable water  / groundwater / surface water

ANALYTE LIST

TARGET ANALYTES
CASRN
SURROGATE ANALYTES
PFBA
375-22-4
M4-PFBA
PFPeA
2706-90-3
M5-PFPeA
PFHxA
307-24-4
M5-PFHxA
PFHpA
375-85-9
M4-PFHpA
PFOA
335-67-1
M8-PFOA
PFNA
375-95-1
M9-PFNA
PFDA
335-76-2
M6-PFDA
PFUnDA
2058-94-8
M7-PFUnDA
PFDoDA
307-55-1
M2-PFDoDA
PFTrDA
72629-94-8
M2-PFTeDA
PFTeDA
376-06-7
M8-PFOSA
PFBS
375-73-5
D3-NMeFOSAA
PFPeS
2706-91-4
D5-NEtFOSAA
PFHxS
355-46-4
M3-PFBS
PFHpS
375-92-8
M3-PFHxS
PFOS
1763-23-1
M8-PFOS
PFNS
68259-12-1
M2-4:2 FTS
PFDS
335-77-3
M2-6:2 FTS
4:2 FTS
757124-72-4
M2-8:2 FTS
6:2 FTS
27619-97-2
xxx
8:2 FTS
39108-34-4
xxx
NMeFOSAA
2355-31-9
xxx
NEtFOSAA
52991-50-6
xxx
PFOSA
754-91-6
xxx

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